Aplastic crisis as primary manifestation of systemic lupus erythematosus.

Hematologic manifestation of systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. The most common hematologic finding is anemia, leukopenia, thrombocytopenia and secondary antiphospholipid syndrome with recurrent abortion and thrombosis. The autoimmune fibrosis of bone marrow is another manifestation of autoimmune disease especially SLE, that must be correctly differentiated from primary myelofibrosis.

Oral contraceptive-related transverse sinus thrombosis as an initial manifestation of antiphospholipid syndrome in the absence of systemic lupus erythematosus

PSEUDO TUMOR CEREBRI AS THE MAJOR MANIFESTATION OF SYSTEMIC LUPUS ER Y THEMATOSUS IN A CASE OF FEVER OF UNDE TERMINED ORIGIN

Systemic lupus erythematosus (SLE) is less likely to present as fever of undetermined origin today. This is due to the widespread use of immunologic tests which permit early diagnosis. It is not surprising therefore that only atypical cases of SLE present as FUa. Although uncommon, pseudotumor cerebri has been recognized as either a presenting manifestation or a complication of SLE. This c...

Codon 72 Polymorphism of p53 Gene and Hematologic Manifestations in Patients with Systemic Lupus Erythematosus

Background: Systemic lupus erythematosus is a systemic autoimmune disorder with unclear etiology. The importance of some genes in the development of systemic lupus erythematosus has been implicated. The gene polymorphism in codon 72 has attracted a lot of attention and its role in the occurrence or progression of many cancers and autoimmune diseases especially systemic lupus erythematosus has ...

Aplastic anemia associated to systemic lupus erythematosus in an AIDS patient: a case report

Aplastic anemia is a bone marrow failure syndrome characterized by peripheral cytopenias and hypocellular bone marrow. Although aplastic anemia is idiopathic in most cases, rheumatic diseases such as systemic lupus erythematosus are recognized as causes of aplastic anemia, with their possible etiological mechanisms being T and B lymphocyte dysfunction and pro-inflammatory cytokines and autoanti...